Angiomatosis

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Angiomatosis
SkinTumors-PB061065.JPG
Skin angiomatosis
Classification and external resources
eMedicine article/1051846
MeSH D000798

Angiomatosis is a non-neoplastic condition[1] characterised by nests of proliferating capillaries arranged in a lobular pattern, displacing adjacent muscle and fat.[2] It consists of many angiomas.[3]

These tend to be cavernous hemangiomas, which are sharply defined, sponge-like tumors composed of large, dilated, cavernous vascular spaces.

Histology[edit]

It is a vascular malformation wherein blood vessels proliferate along with accompanying mature fat and fibrous tissue, lymphatics and sometimes nerves.[2] They may involve skin, subcutaneous tissue, skeletal muscle and occasionally bone.[2]

Associated syndromes[edit]

They often appear in:

Prognosis[edit]

Prognosis depends on the size and location of the tumour, untreated angiomatosis may lead to blindness and/ or permanent brain damage. Death may occur, with complications in the kidney or brain.<ref name="NINDS Info Page"/ >

See also[edit]

References[edit]

  1. ^ Angiomatosis at the US National Library of Medicine Medical Subject Headings (MeSH)
  2. ^ a b c Howat, AJ; Campbell, PE (October 1987). "Angiomatosis: a vascular malformation of infancy and childhood. Report of 17 cases". Pathology. 19 (4): 377–82. PMID 3444663. 
  3. ^ "angiomatosis" at Dorland's Medical Dictionary
  4. ^ "Von Hippel-Lindau Disease (VHL) Information Page". www.ninds.nih.gov. National Institute of Neurological Disorders and Stroke.