Angiopoietin-related protein 2

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ANGPTL2
Identifiers
Aliases ANGPTL2, ARP2, HARP, angiopoietin like 2
External IDs MGI: 1347002 HomoloGene: 22695 GeneCards: 23452
RNA expression pattern
PBB GE ANGPTL2 213001 at tn.png

PBB GE ANGPTL2 213004 at tn.png

PBB GE ANGPTL2 219514 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_012098

NM_011923

RefSeq (protein)

NP_036230.1

NP_036053.2

Location (UCSC) Chr 9: 127.09 – 127.12 Mb Chr 2: 33.22 – 33.25 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Angiopoietin-related protein 2 also known as angiopoietin-like protein 2 is a protein that in humans is encoded by the ANGPTL2 gene.[3][4]

Function[edit]

Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 protein is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Kim I, Moon SO, Koh KN, Kim H, Uhm CS, Kwak HJ, Kim NG, Koh GY (Oct 1999). "Molecular cloning, expression, and characterization of angiopoietin-related protein. angiopoietin-related protein induces endothelial cell sprouting". J Biol Chem. 274 (37): 26523–8. doi:10.1074/jbc.274.37.26523. PMID 10473614. 
  4. ^ a b "Entrez Gene: ANGPTL2 angiopoietin-like 2". 

Further reading[edit]