Anhydrosialidase

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Anhydrosialidase
Identifiers
EC number 4.2.2.15
CAS number 157857-11-9
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

In enzymology, an anhydrosialidase (EC 4.2.2.15) is an enzyme that catalyzes the chemical reaction

Elimination of alpha-sialyl groups in N-acetylneuraminic acid glycosides, releasing 2,7-anhydro-alpha-N-acetylneuraminate

This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The systematic name of this enzyme class is glycoconjugate sialyl-lyase (2,7-cyclizing). Other names in common use include anhydroneuraminidase, sialglycoconjugate N-acylneuraminylhydrolase (2,7-cyclizing), and sialidase L.

References[edit]

  • Li YT, Nakagawa H, Ross SA, Hansson GC, Li SC (1990). "A novel sialidase which releases 2,7-anhydro-alpha-N-acetylneuraminic acid from sialoglycoconjugates". J. Biol. Chem. 265 (35): 21629–33. PMID 2254319.