Anisodamine

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Anisodamine
Anisodamine.svg
Clinical data
ATC code
  • None
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ECHA InfoCard100.164.962 Edit this at Wikidata
Chemical and physical data
FormulaC17H23NO4
Molar mass305.37 g/mol g·mol−1
3D model (JSmol)
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Anisodamine, also known as 7β-hydroxyhyoscyamine, is an anticholinergic and α1 adrenergic receptor antagonist used in the treatment of acute circulatory shock in China.[1] It is given orally or by injection, as a racemic mixture (racanisodamine) or as a hydrobromide salt.[2] Eye drops at 0.5% concentration for slowing the progression is also available in China.[3]

Anisodamine is a naturally occurring tropane alkaloid found in some plants of the Solanaceae family.[4] Its Mandarin Chinese name 山莨菪 is given after Anisodus tanguticus (Chinese: ; pinyin: shān làng dàng).[5]

See also[edit]

References[edit]

  1. ^ Varma DR, Yue TL (March 1986). "Adrenoceptor blocking properties of atropine-like agents anisodamine and anisodine on brain and cardiovascular tissues of rats". British Journal of Pharmacology. 87 (3): 587–94. doi:10.1111/j.1476-5381.1986.tb10201.x. PMC 1916562. PMID 2879586.
  2. ^ "Pharmacopoeia Search: "山莨菪碱"". 中国药典.
  3. ^ "消旋山莨菪碱滴眼液防治少年儿童假性近视的疗效分析". 国际医药卫生导报 (in Chinese). 14 (15): 67–68. 2008. doi:10.3760/cma.j.issn.1007-1245.2008.15.027.
  4. ^ Zhang WW, Song MK, Cui YY, et al. (October 2008). "Differential neuropsychopharmacological influences of naturally occurring tropane alkaloids anisodamine versus scopolamine". Neuroscience Letters. 443 (3): 241–5. doi:10.1016/j.neulet.2008.07.048. PMID 18672024.
  5. ^ "消旋山莨菪碱" (in Chinese). 中国药典. Archived from the original on 2017-12-03. Retrieved 3 December 2017.