Prior to April 2007, the train operated as number 303 eastbound and 304 westbound between Chicago and Kansas City via St. Louis over the full 567-mile (912 km) route. After April 2007 the Ann Rutledge operated daily between St. Louis and Kansas City connecting to the Illinois Amtrak Lincoln Service at St. Louis. Its last numbers were 313 westbound and 314 eastbound.
Amtrak revived the name Ann Rutledge on February 15, 1976 for an Amfleet-equipped train on the St. Louis-Chicago, replacing a Turboliner frequency. The revival proved short-lived: on October 31 Amtrak extended the Laredo-St. LouisInter-American through to Chicago, replacing the Ann Rutledge. In a reversal of the situation with the Alton in the 1930s, Amtrak used the Ann Rutledge's Amfleet coaches to re-equip a revived Abraham Lincoln. Amtrak revived the name again on October 30, 1977, replacing the Abraham Lincoln.:229 Finally satisfied with the name, Amtrak operated the Ann Rutledge until 2009.