Pastore studied chemistry at the University of Naples Federico II. She earned a master's degree in 1981 and her PhD in 1987. She worked as an exchange student with Richard R. Ernst at ETH Zurich and also at the University of Wisconsin.
Pastore started her career at the University of Oxford as a postdoctoral fellow in the Department of Biochemistry, working alongside Iain Donald Campbell. Pastore was subsequently appointed a staff scientist position at European Molecular Biology Laboratory in 1988. In 1991 she was made group leader of the Structures Program. She joined the National Institute for Medical Research in 1991. She has solved several structures on the Protein Data Bank. She was made an honorary professor at University College London.  She took a one-year sabbatical at the French National Institute for Agricultural Research. During this time, she filed several patents related to allergens and their uses.
Pastore worked at King's College London from 2013 to 2018. She has secured several million pounds of funding from Medical Research Council and the Biotechnology and Biological Sciences Research Council. She works on the molecular basis of neurodegeneration. She looks at diseases caused by protein aggregation, including Huntington's disease and Machado–Joseph disease. She also studies pathologies that are a result of misfunctioning of the iron metabolism, including Friedreich's ataxia. She is interested the structure and function of these diseases and uses a range of characterisation techniques, including AFM, EM and ITC calorimetry. She served as the Field Chief Editor for Frontiers Media Molecular Biosciences. She serves as an editor of PeerJ.
Awards and honours
Pastore was elected a member of the Academia Europaea (MAE).[when?] She was nominated to AcademiaNet in 2013 and made a member of the European Molecular Biology Organization (EMBO) in 2000.
- "EMBO MEMBER: Annalisa Pastore". people.embo.org. Retrieved 2018-10-20.
- Ehrnhoefer, Dagmar E; Bieschke, Jan; Boeddrich, Annett; Herbst, Martin; Masino, Laura; Lurz, Rudi; Engemann, Sabine; Pastore, Annalisa; Wanker, Erich E (2008). "EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers". Nature Structural & Molecular Biology. 15 (6): 558–566. doi:10.1038/nsmb.1437. ISSN 1545-9993. PMID 18511942.
- Annalisa Pastore publications indexed by Google Scholar
- Annalisa Pastore publications indexed by the Scopus bibliographic database. (subscription required)
- "Pisa, la prima prof ordinaria di Scienze nella storia della Normale: "Anche contro di me offese sessiste" - Il Fatto Quotidiano". Il Fatto Quotidiano (in Italian). 2018-10-18. Retrieved 2018-10-20.
- "Annalisa Pastore". Loop. Retrieved 2018-10-20.
- Cooke, Robert M.; Wilkinson, Anthony J.; Baron, Martin; Pastore, Annalisa; Tappin, Michael J.; Campbell, Iain D.; Gregory, Harry; Sheard, Brian (1987). "The solution structure of human epidermal growth factor". Nature. 327 (6120): 339–341. Bibcode:1987Natur.327..339C. doi:10.1038/327339a0. ISSN 0028-0836. PMID 3495735.
- "PeerJ - Profile - Annalisa Pastore". peerj.com. Retrieved 2018-10-20.
- EMBL. "Alumni News - March 2009 - NMR alumni celebrate opening of NMR centre at EMBL Heidelberg - EMBL". www.embl.es. Retrieved 2018-10-20.
- "Annalisa Pastore Inventions, Patents and Patent Applications - Justia Patents Search". patents.justia.com. Retrieved 2018-10-20.
- "King's College London - Annalisa Pastore Group". www.kcl.ac.uk. Retrieved 2018-10-20.
- "Annalisa Pastore". Retrieved 2018-10-20.
- "Annalisa Pastore - Research Portal, King's College, London". kclpure.kcl.ac.uk. Retrieved 2018-10-20.
- Frontiers (2016-02-16), Frontiers Science Hero Annalisa Pastore, retrieved 2018-10-20
- Tebano, di Elena. "Scuola Normale, Annalisa Pastore è la prima ordinaria di scienze: "Il sessismo? Esiste"". Corriere della Sera (in Italian). Retrieved 2018-10-20.
- Hoffmann, Ilire Hasani, Robert. "Academy of Europe: Pastore Annalisa". www.ae-info.org. Retrieved 2018-10-20.
- "Prof. Annalisa Pastore - AcademiaNet". www.academia-net.org. Retrieved 2018-10-20.