Annexin A3

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ANXA3
Protein ANXA3 PDB 1aii.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases ANXA3, ANX3, annexin A3
External IDs MGI: 1201378 HomoloGene: 68445 GeneCards: ANXA3
RNA expression pattern
PBB GE ANXA3 209369 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005139

NM_013470

RefSeq (protein)

NP_005130

NP_038498.2
NP_038498

Location (UCSC) Chr 4: 78.55 – 78.61 Mb Chr 5: 96.79 – 96.85 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Annexin A3 is a protein that in humans is encoded by the ANXA3 gene.[3][4]

It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to the increase risk of birth defects in these ART.[5]

This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phospholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Tait JF, Frankenberry DA, Miao CH, Killary AM, Adler DA, Disteche CM (Aug 1991). "Chromosomal localization of the human annexin III (ANX3) gene". Genomics. 10 (2): 441–8. doi:10.1016/0888-7543(91)90330-H. PMID 1830024. 
  4. ^ a b "Entrez Gene: ANXA3 annexin A3". 
  5. ^ Zhang Y, Zhang YL, Feng C, et al. (September 2008). "Comparative proteomic analysis of human placenta derived from assisted reproductive technology". Proteomics. 8 (20): 4344–56. doi:10.1002/pmic.200800294. PMID 18792929. 

External links[edit]

Further reading[edit]