Anordiol

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Anordiol
Anordiol.png
Clinical data
SynonymsAnordriol; 2α,17α-Diethynyl-A-nor-5α-androstane-2β,17β-diol
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC22H30O2
Molar mass326.48 g/mol g·mol−1
3D model (JSmol)

Anordiol, or anordriol, also known as 2α,17α-diethynyl-A-nor-5α-androstane-2β,17β-diol, is a synthetic steroid-like mixed estrogen and antiestrogen and an active metabolite of anordrin, a postcoital contraceptive that is marketed and used in China.[1][2][3] Relative to anordrin, anordiol has similar but more potent actions.[1][2]

References[edit]

  1. ^ a b Michael Oettel; Ekkehard Schillinger (6 December 2012). Estrogens and Antiestrogens II: Pharmacology and Clinical Application of Estrogens and Antiestrogen. Springer Science & Business Media. pp. 545–. ISBN 978-3-642-60107-1.
  2. ^ a b Chatterton RT, Berman C, Walters NN (1989). "Anti-uterotrophic and folliculostatic activities of anordiol (2 alpha,17 alpha-diethynyl-A-nor-5 alpha-androstane-2 beta,17 beta-diol)". Contraception. 39 (3): 291–7. doi:10.1016/0010-7824(89)90061-9. PMID 2714089.
  3. ^ Peters AJ, Wentz AC, Kazer RR, Jeyendran RS, Chatterton RT (1995). "Estrogenic and antiestrogenic activities of anordiol: a comparison of uterine and vaginal responses with those of clomiphene citrate". Contraception. 52 (3): 195–202. PMID 7587192.