Anterior nuclei of thalamus
|Anterior nuclei of thalamus|
MNG = Midline nuclear group
AN = Anterior nuclear group
MD = Medial dorsal nucleus
VNG = Ventral nuclear group
VA = Ventral anterior nucleus
VL = Ventral lateral nucleus
VPL = Ventral posterolateral nucleus
VPM = Ventral posteromedial nucleus
LNG = Lateral nuclear group
PUL = Pulvinar
MTh = Metathalamus
LG = Lateral geniculate nucleus
MG = Medial geniculate nucleus
|Latin||Nuclei anteriores thalami|
|NeuroLex ID||Anterior Nuclear Group|
|Anatomical terms of neuroanatomy|
Inputs and outputs
The anterior nuclei of the thalamus display functions pertaining to memory. Persons displaying lesions in the anterior thalamus, preventing input from the pathway involving the hippocampus, mammillary bodies and the MTT, display forms of amnesia, supporting the anterior thalamus's involvement in episodic memory. However, although the hypothalamus projects to both the mammillary bodies and the anterior nuclei of the thalamus, the anterior nuclei receive input from hippocampal cells deep to the pyramidal cells projecting to the mammillary bodies.
These nuclei are considered to be association nuclei, one of the three broader subdivisions of thalamic nuclei. These nuclei receive input from the cerebral cortex. The input received is integrated and re-directed back to the cortical areas of the cerebrum known as association areas. The anterior nuclei regulates what input is redistributed to the cortex. The connections of the anterior nuclei are similar to that of the lateral dorsal (LD) nuclei. 
The anterior thalamic nuclei (ATN) are recently thought to be connected in pathways serving a spatial navigation role in reference to propagating head movements. The ATN displays bidirectional connections with the postsubiculum, a structure in humans involved in regulating signaling relative to the movement of the head in the horizontal plane. This structure contains "head direction cells" hypothesized to also be present in the ATN. These head direction cells fire in response to an animal pointing its head in a certain direction. Ultimately, the firing sequences of these cells encode information allowing an animal to perceive its direction in relation to its spatial environment.
- Dere, Ekrem; Easton, Alexander; Nadel, Lynn; Huston, Joseph (2008). Handbook of Episodic Memory. Elsevier B.V. pp. 512–513. ISBN 978-0-444-53174-2. Retrieved 6 July 2015.
- Swenson, Rand (2006). Review of Clinical and Functional Neuroscience. Dartmouth Medical School. Retrieved July 6, 2015.
- Child, ND; Benarroch, EE (19 November 2013). "Anterior nucleus of the thalamus: functional organization and clinical implications". Neurology 81 (21): 1869–1976. doi:10.1212/01.wnl.0000436078.95856.56. ISSN 1526-632X.
- Jankowski, Maciej; Ronnqvist, Kim; Tsanov, Marian; Vann, Seralynne; Wright, Nicholas; Erichsen, Johnathan; Aggleton, John; O'Mara, Shane (30 August 2013). "The Anterior Thalamus Provides a Subcortical Circuit Supporting Memory and Spatial Navigation". Frontiers in Systems Neuroscience 7. doi:10.3389/fnsys.2013.00045. Retrieved 6 July 2015.
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