Anthony L. Komaroff

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Anthony Komaroff
Tony Komaroff.jpg
Born (1941-06-07) June 7, 1941 (age 81)
Alma materStanford University (A.B.), University of Washington (M.D.)
Spouse(s)Lydia Villa-Komaroff
Scientific career
FieldsGeneral internal medicine, Clinical epidemiology
InstitutionsHarvard Medical School, Brigham and Women’s Hospital

Anthony L. Komaroff (born June 7, 1941) is an American physician, clinical investigator, editor, and publisher. He serves as the Distinguished Simcox-Clifford-Higby Professor of Medicine at Harvard Medical School and Senior Physician at Brigham and Women's Hospital in Boston.

Early life[edit]

Anthony L. (Tony) Komaroff was raised in Los Angeles, California. He attended college at Stanford University and medical school at the University of Washington in Seattle.


Following medical school, he received training in internal medicine at Harvard Medical School and then joined the faculty.

Komaroff was the Director of the Division of General Medicine and Primary Care at Brigham & Women's Hospital, Boston MA, from 1982 to 1997, and built one of the world’s renowned academic general medicine units. From 1982 to 1987, he was the vice president for management systems of Brigham and Women's Hospital, with oversight of the Hospital's computer systems. From 1997 through January 2015, he served as Editor-in-Chief of the Harvard Health Publications Division (HHP) of Harvard Medical School, the division responsible for publishing all of the School's health information for the general public—books, newsletters, Internet content and doctors' office information. The information is published in multiple languages, in countries around the world [1].

Komaroff has published over 280 research articles and book chapters, and two books. His early publications cover the development of clinical algorithms,[1][2] cost-effectiveness analyses of primary care practices,[3] and clinical research on common respiratory and urinary infections,.[4][5] In recent decades, Dr. Komaroff’s research has focused on chronic fatigue syndrome[6][7][8][9][10][11][12] and also on human herpesvirus 6.[13][14][15]

Komaroff was the Editor in Chief of the best-selling book, the Harvard Medical School Family Health Guide;[16] is the founding editor of NEJM Journal Watch, a publication of the New England Journal of Medicine [2]; is the editor-in-chief of the Harvard Health Letter, a newsletter from Harvard Medical School for the general public [3]; and from 2011-December 2016 was the author of a daily newspaper column, Ask Doctor K, that was syndicated by United Media and appeared in over 400 newspapers in North America. In these publications, and in medical journals, he describes the latest developments in biological science and medical research to both practicing health professionals and the general public.[17][18][19][20][21]

Finally, Komaroff also served as editor of the autobiographies of two biomedical scientists, Nobel Laureates Joseph E. Murray[22] and Thomas H. Weller.[23]

Komaroff serves as the Distinguished Simcox-Clifford-Higby Professor of Medicine at Harvard Medical School and Senior Physician at Brigham and Women's Hospital in Boston [4].



  1. ^ Komaroff, AL; Black, WL; Flatley, M; Knopp, RH; Reiffen, B; Sherman, H (1974). "Protocols for physician assistants. Management of diabetes and hypertension". The New England Journal of Medicine. 290 (6): 307–12. doi:10.1056/NEJM197402072900605. PMID 4148936.[non-primary source needed]
  2. ^ Greenfield, S; Komaroff, AL; Pass, TM; Anderson, H; Nessim, S (1978). "Efficiency and cost of primary care by nurses and physician assistants". The New England Journal of Medicine. 298 (6): 305–9. doi:10.1056/NEJM197802092980604. PMID 23495.[non-primary source needed]
  3. ^ Berwick, DM; Komaroff, AL (1982). "Cost effectiveness of lead screening". The New England Journal of Medicine. 306 (23): 1392–8. doi:10.1056/NEJM198206103062304. PMID 6804866.[non-primary source needed]
  4. ^ Komaroff, AL.; Aronson, M.; Pass, T.; Ervin, C.; Branch, W.; Schachter, J (1983). "Serologic evidence of chlamydial and mycoplasmal pharyngitis in adults". Science. 222 (4626): 927–9. doi:10.1126/science.6415813. PMID 6415813.[non-primary source needed]
  5. ^ Komaroff, AL.; Friedland, G (1980). "The Dysuria-Pyuria Syndrome". New England Journal of Medicine. 303 (8): 452–4. doi:10.1056/NEJM198008213030808. PMID 6893073.[non-primary source needed]
  6. ^ Komaroff, AL (2015). "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Real Illness". Annals of Internal Medicine. 162 (12): 871–2. doi:10.7326/m15-0647. PMID 26075760.
  7. ^ Komaroff, AL (2017). "Inflammation correlates with symptoms in chronic fatigue syndrome". Proceedings of the National Academy of Sciences USA. 114 (34): 8914–6. doi:10.1073/pnas.1712475114. PMC 5576849. PMID 28811366.
  8. ^ Komaroff, AL (2019). "Advances in understanding the pathophysiology of chronic fatigue syndrome". JAMA. 322 (6): 499–500. doi:10.1001/jama.2019.8312. PMID 31276153. S2CID 195805355.
  9. ^ Nagy-Szakal, D (2018). "Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics". Scientific Reports. 8 (1): 10056. doi:10.1038/s41598-018-28477-9. PMC 6030047. PMID 29968805.
  10. ^ Komaroff, AL (2021). "Insights from myalgic encephalomyelitis/chronic fatigue syndrome may help unravel the pathogenesis of post-acute COVID-19 syndrome". Trends in Molecular Medicine. 27 (9): 895–906. doi:10.1016/j.molmed.2021.06.002. S2CID 235354169.
  11. ^ Paul, B (2021). "Redox imbalance links COVID-19 and myalgic encephalomyelitis/chronic fatigue syndrome". Proceedings of the National Academy of Sciences USA. 118 (34): e2024358118. doi:10.1073/pnas.2024358118. PMC 8403932. PMID 34400495.
  12. ^ Komaroff, AL (2021). "Will COVID-19 lead to myalgic encephalomyelitis/chronic fatigue syndrome?". Frontiers in Medicine. 7: 606824. doi:10.3389/fmed.2020.606824. PMC 7848220. PMID 33537329.
  13. ^ Arbuckle, JH; et al. (2010). "The latent human herpesvirus-6A genome specifically integrates in telomeres of human chromosomes in vivo and in vitro". Proceedings of the National Academy of Sciences USA. 107 (12): 5563–8. doi:10.1073/pnas.0913586107. PMC 2851814. PMID 20212114.
  14. ^ Komaroff, AL (2020). "Human herpesviruses 6A and 6B in brain diseases: association versus causation". Clinical Microbiology Reviews. 34 (1): e00143-20. doi:10.1128/CMR.00143-20. PMC 7667666. PMID 33177186.
  15. ^ Komaroff, AL (2021). "Human herpesviruses 6A and 6B in reproductive diseases". Frontiers in Immunology. 12: 648945. doi:10.3389/fimmu.2021.648945. PMC 8027340. PMID 33841432.
  16. ^ Komaroff, Anthony L. (1999). Harvard Medical School Family Health Guide. Simon & Schuster.
  17. ^ Komaroff, AL (2017). "The microbiome and risk for obesity and diabetes". JAMA. 317 (4): 355–6. doi:10.1001/jama.2016.20099. PMID 28006047. S2CID 5078210.
  18. ^ Komaroff, AL (2017). "Gene editing using CRISPR: why the excitement?". JAMA. 318 (8): 699–700. doi:10.1001/jama.2017.10159. PMID 28796848.
  19. ^ Komaroff, AL (2020). "Can infections cause Alzheimer disease?". JAMA. 324 (3): 239–40. doi:10.1001/jama.2020.4085. S2CID 219548603.
  20. ^ Komaroff, AL (2021). "Does sleep flush wastes from the brain?". JAMA. 325 (21): 2153–4. doi:10.1001/jama.2021.5631. PMID 33999096. S2CID 234747224.
  21. ^ Komaroff, AL (2021). "Breakthrough discovery in protein structure prediction and the promise of new treatments". JAMA. 326 (14): 1369–70. doi:10.1001/jama.2021.15728. PMID 34554183. S2CID 237608592.
  22. ^ Murray, Joseph E. (2001). Surgery of the Soul. Science History Publications USA.
  23. ^ Weller, Thomas H. (2004). Growing Pathogens in Tissue Cultures. Science History Publications USA.

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