Anti-smooth muscle antibody

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Anti-smooth muscle antibodies are antibodies (immunoglobulins) formed against smooth muscle. These antibodies are typically associated with autoimmune hepatitis.[1][2]

These antibodies can be directed against actin, troponin, and tropomyosin.[3]


  1. ^ Dawkins, RL; Joske RA (June 1973). "Immunoglobulin deposition in liver of patients with active chronic hepatitis and antibody against smooth muscle". British Medical Journal. 2 (5867): 643–645. doi:10.1136/bmj.2.5867.643. PMC 1589647Freely accessible. PMID 4577016. 
  2. ^ M. Eric Gershwin (2007). Liver immunology: principles and practice. Humana Press. pp. 265–. ISBN 978-1-58829-818-8. Retrieved 26 October 2010. 
  3. ^ Kenneth Michael Pollard (2006). Autoantibodies and autoimmunity: molecular mechanisms in health and disease. Wiley-VCH. pp. 293–. ISBN 978-3-527-31141-5. Retrieved 26 October 2010.