|Synonyms||Glucocorticoid antagonist; Cortisol antagonist; Anticorticosteroid|
|Use||Cushing's syndrome, others|
|Biological target||Glucocorticoid receptor|
An antiglucocorticoid is a drug which reduces glucocorticoid activity in the body. They include direct glucocorticoid receptor antagonists such as mifepristone and synthesis inhibitors such as metyrapone, ketoconazole, and aminoglutethimide. They are used to treat Cushing's syndrome.
- Gallagher P, Malik N, Newham J, Young AH, Ferrier IN, Mackin P (2008). "Antiglucocorticoid treatments for mood disorders". Cochrane Database of Systematic Reviews (1): CD005168. doi:10.1002/14651858.CD005168.pub2. PMID 18254070.
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