A former motocross rider, he debuted in the World Enduro Championship in 2008 with Husqvarna, where he placed fifth. In the following year, Méo finished second to Mika Ahola in the E1 category. Continuing with Husqvarna, he won the world title in 2010 ahead of countryman Johnny Aubert. For the 2011 season, Méo moved to the E2 class and claimed his second title. He returned to the E1 class, winning the 2012 and 2013 titles with KTM.
In 2009 and 2010, he won the International Six Days Enduro (ISDE) World Trophy with the French national team.
Méo also won the Italian round of the 2007/08 FIM Indoor Enduro World Cup. In 2009/10 he got a second-place finish at the first race in Great Britain.
He competed in the 2016 Dakar Rally, a rally raid competition which takes place annually in South America, riding for the factory Red Bull KTM team. In his first attempt he won the 11th stage and finished 7th overall.
|2002||European Supercross Championship||125 cc||Kawasaki||?||1st|
|2003||French Motocross Championship||250 cc||Kawasaki||?||2nd|
|2004||Motocross World Championship||MX1||Kawasaki||0||15th|
|2005||Motocross World Championship||MX1||Husqvarna||0||20th|
|2008||World Enduro Championship||E2||Husqvarna||0||5th|
|2009||World Enduro Championship||E1||Husqvarna||6||2nd|
|2010||World Enduro Championship||E1||Husqvarna||8||1st|
|2011||World Enduro Championship||E2||Husqvarna||8||1st|
|2012||World Enduro Championship||E1||KTM||12||1st|
|2013||World Enduro Championship||E1||KTM||12||1st|
|2009||Figueira da Foz, Portugal||World Trophy||France||1st|
|2010||Morelia, Mexico||World Trophy||France||1st|
- "Rider: MEO Antoine". enduro-abc.com. Retrieved 10 October 2011.
- "Husqvarna's Antoine Meo Is The 2011 Enduro 2 World Champion". Londonbikers.com. 7 September 2011. Archived from the original on 17 October 2011. Retrieved 10 October 2011.
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