In 1890 he earned his medical degree in Graz, and afterwards spent several years at the pathological institute in Vienna, where he worked with Anton Weichselbaum (1845–1920). In 1910 he became a professor of pathological anatomy at the German University in Prague.
Ghon was a specialist in the field of bacteriology, and is remembered for his work with meningitis and tuberculosis. His name is lent to Ghon focus, which is a primary infection associated with tuberculosis, as well as Ghon's complex — when the aforementioned infection involves surrounding lymph nodes. His best written effort is a 1912 treatise of childhood tuberculosis called "Der primäre Lungenherd bei der Tuberkulose der Kinder".
- Der primäre Lungenherd bei der Tuberkulose der Kinder, (1912).
- Publications about Anton Ghon:
- "Ghon, but not forgotten, (Anton Ghon and his complex)"; WB Ober (1983).
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