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Antzitene or Anzitene (error: {{lang-xx}}: text has italic markup (help), Greek: Ἀνζιτηνή) was a region of the medieval Armenia c. 300–1000, known in Armenian as Hanzith and in Syriac as Hanzit.

From 384, it formed one of the satrapies of Roman Armenia, before becoming part of the new province of Armenia IV in 536. In the 10th century the rulers were Habel (c. 970) and Sahak (c. 995).

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