An aphrodisiac or love drug is a substance that increases libido when consumed. Aphrodisiacs are distinct from substances that address fertility issues or secondary sexual (dys)function such as erectile dysfunction.
The name comes from the Greek ἀφροδισιακόν, aphrodisiakon, i.e. "sexual, aphrodisiac", from aphrodisios, i.e. "pertaining to Aphrodite", the Greek goddess of love. The opposite substance is an anaphrodisiac.
Assessment of aphrodisiac qualities
Throughout human history, food, drinks, and behaviors have had a reputation for making sex more attainable and/or pleasurable. However, from a historical and scientific standpoint, the alleged results may have been mainly due to mere belief by their users that they would be effective (placebo effect). Likewise, many medicines are reported to affect libido in inconsistent or idiopathic ways:  enhancing or diminishing overall sexual desire depending on the situation of subject. For example, Bupropion (Wellbutrin) is known as an antidepressant that can counteract other co-prescribed antidepressants having libido-diminishing effects. However, because Wellbutrin only increases the libido in the special case that it is already impaired by related medications, it is not generally classed as an aphrodisiac.
Yohimbine, Spanish fly, mad honey, and bufo toad have no scientific evidence of providing aphrodisiac effects. While numerous plants, extracts or manufactured hormones have been proposed as aphrodisiacs, there is little high-quality clinical evidence for the efficacy or long-term safety of using them.
Libido in males is linked to levels of sex hormones, particularly testosterone. When a reduced sex drive occurs in individuals with relatively low levels of testosterone, particularly in postmenopausal women or men over age 60, testosterone dietary supplements have been used with intent to increase libido, although with limited benefit. Long-term therapy with oral testosterone is associated with increased risk of cardiovascular diseases.
Amphetamine and methamphetamine are phenethylamine derivatives which are known to increase libido and cause frequent or prolonged erections as potential side effects, particularly at high supratherapeutic doses where sexual hyperexcitability and hypersexuality can occur; however, in some individuals who use these drugs, libido is reduced.
In popular culture
The invention of an aphrodisiac is the basis of a number of films including Perfume: The Story of a Murderer, Spanish Fly, She'll Follow You Anywhere, Love Potion No. 9 and A Serbian Film. The first segment of Woody Allen's Everything You Always Wanted to Know About Sex* (*But Were Afraid to Ask) is called "Do Aphrodisiacs Work?", and casts Allen as a court jester trying to seduce the queen.
- ἀφροδισιακόν. Liddell, Henry George; Scott, Robert; A Greek–English Lexicon at the Perseus Project.
- "Aphrodisiac". Online Etymology Dictionary.
- West E, Krychman M (October 2015). "Natural Aphrodisiacs-A Review of Selected Sexual Enhancers". Sex Med Rev. 3 (4): 279–288. doi:10.1002/smrj.62. PMID 27784600.
- "Sexual health". Drugs.com. 11 June 2016. Retrieved 17 May 2018.
- R. Shabsigh (1997). "The effects of testosterone on the cavernous tissue and erectile function". World J. Urol. 15 (1): 21–6. doi:10.1007/BF01275152. PMID 9066090.
- Fisher, Helen E.; Aron, Arthur; Brown, Lucy L. (2006-12-29). "Romantic love: a mammalian brain system for mate choice". Philosophical Transactions of the Royal Society of London B: Biological Sciences. 361 (1476): 2173–2186. doi:10.1098/rstb.2006.1938. ISSN 0962-8436. PMC . PMID 17118931.
- Snyder, P. J; Bhasin, S; Cunningham, G. R; Matsumoto, A. M; Stephens-Shields, A. J; Cauley, J. A; Gill, T. M; Barrett-Connor, E; Swerdloff, R. S; Wang, C; Ensrud, K. E; Lewis, C. E; Farrar, J. T; Cella, D; Rosen, R. C; Pahor, M; Crandall, J. P; Molitch, M. E; Cifelli, D; Dougar, D; Fluharty, L; Resnick, S. M; Storer, T. W; Anton, S; Basaria, S; Diem, S. J; Hou, X; Mohler Er, I. I. I; Parsons, J. K; et al. (2016). "Effects of Testosterone Treatment in Older Men". New England Journal of Medicine. 374 (7): 611–624. doi:10.1056/NEJMoa1506119. PMC .
- Borst, S. E; Shuster, J. J; Zou, B; Ye, F; Jia, H; Wokhlu, A; Yarrow, J. F (2014). "Cardiovascular risks and elevation of serum DHT vary by route of testosterone administration: A systematic review and meta-analysis". BMC Medicine. 12: 211. doi:10.1186/s12916-014-0211-5. PMC . PMID 25428524.
- Gunne LM (2013). "Effects of Amphetamines in Humans". Drug Addiction II: Amphetamine, Psychotogen, and Marihuana Dependence. Berlin, Germany; Heidelberg, Germany: Springer. pp. 247–260. ISBN 9783642667091. Retrieved 4 December 2015.
- "Adderall XR Prescribing Information" (PDF). United States Food and Drug Administration. December 2013. pp. 4–8. Retrieved 30 December 2013.
- Montgomery KA (June 2008). "Sexual desire disorders". Psychiatry (Edgmont). 5 (6): 50–55. PMC . PMID 19727285.
- "Desoxyn Prescribing Information" (PDF). United States Food and Drug Administration. December 2013. Retrieved 6 January 2014.
ADVERSE REACTIONS ... changes in libido; frequent or prolonged erections. [emphasis added]
- Gabriele Froböse, Rolf Froböse, Michael Gross (Translator): Lust and Love: Is it more than Chemistry?
- Michael Scott: "Pillow Talk: A Comprehensive Guide to Erotic Hypnosis and Relyfe Programming"
- Media related to Aphrodisiacs at Wikimedia Commons
- Aphrodisiacs and Anti-aphrodisiacs: Three Essays on the Powers of Reproduction by John Davenport.