Apicidin

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Apicidin
Apicidin.svg
Names
IUPAC name
(3S,6S,9S,15aR)-9-[(2S)-2-Butanyl]-6-[(1-methoxy-1H-indol-3-yl)methyl]-3-(6-oxooctyl)octahydro-2H-pyrido[1,2-a][1,4,7,10]tetraazacyclododecine-1,4,7,10(3H,12H)-tetrone
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.163.614
Properties
C34H49N5O6
Molar mass 623.79 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Apicidin is a fungal metabolite, as well as a histone deacetylase inhibitor.[1]

References[edit]

  1. ^ "Apicidin, a histone deacetylase inhibitor, inhibits proliferation of tumor cells via induction of p21WAF1/Cip1 and gelsolin". Cancer Res. 60 (21): 6068–74. November 2000. PMID 11085529.