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Map of Approuague River in French Guiana.

The Approuague river (or Apuruaque in Tupi) is a major river in French Guiana. It runs north from the Tumuk Humak Mountains to the Atlantic Ocean, almost parallel with the Oiapoque, with its mouth by the Pointe Béhague cape.

The Approuague Bridge is 2 kilometres (1.2 mi) south (upstream) of Régina.

Coordinates: 4°21′02″N 52°00′48″W / 4.35052°N 52.01340°W / 4.35052; -52.01340