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In pathology, an apudoma is an endocrine tumour that arises from an APUD cell[1][2] from structures such as the ampulla of Vater.[3] They were historically thought to be derived from neural crest cells,[4] but this has since been shown to be untrue (see neuroendocrine tumor).

The term dates back to at least 1975.[5] Because the label "Apudoma" is very general, it is preferred to use a more specific term when possible.[citation needed]

See also[edit]


  1. ^ Welbourn RB (1977). "Current status of the apudomas". Ann. Surg. 185 (1): 1–12. doi:10.1097/00000658-197701000-00001. PMC 1396259Freely accessible. PMID 12724.  Full Free Text
  2. ^ Fukunaga Y, Hirata S, Tanimura S, et al. (2000). "Superficial undifferentiated small cell carcinoma of the esophagus showing an interesting growing pattern in histology". Hepatogastroenterology. 47 (32): 429–32. PMID 10791205. 
  3. ^ Galati G, Fiori E, Tiziano G, et al. (2002). "[Apudoma of Vater's ampulla: case report and review of the literature]". Il Giornale di chirurgia (in Italian). 23 (3): 97–100. PMID 12109233. 
  4. ^ "eMedicine - VIPoma : Article by Robert J Ferry, Jr, MD". Archived from the original on 16 August 2007. Retrieved 2007-09-22. 
  5. ^ Spence RW, Burns-Cox CJ (1975). "ACTH-secreting 'apudoma' of gallbladder". Gut. 16 (6): 473–6. doi:10.1136/gut.16.6.473. PMC 1411036Freely accessible. PMID 168130. 

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