Aquaporin 3

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AQP3
Identifiers
Aliases AQP3, AQP-3, GIL, aquaporin 3 (Gill blood group)
External IDs OMIM: 600170 MGI: 1333777 HomoloGene: 21025 GeneCards: 360
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004925
NM_001318144

NM_016689

RefSeq (protein)

NP_004916.1
NP_001305073.1

NP_057898.2

Location (UCSC) Chr 9: 33.44 – 33.45 Mb Chr 4: 41.09 – 41.1 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Aquaporin 3 is found in the basolateral cell membrane of principal collecting duct cells and provide a pathway for water to exit these cells.[3] In the kidney, AQP3 gene expression is not regulated by vasopressin (ADH).[4] This protein is also a determinant for the GIL blood group system.[5]

See also[edit]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Sasaki S, Ishibashi K, Marumo F (1998). "Aquaporin-2 and -3: representatives of two subgroups of the aquaporin family colocalized in the kidney collecting duct". Annu. Rev. Physiol. 60: 199–220. doi:10.1146/annurev.physiol.60.1.199. PMID 9558461. 
  4. ^ Dibas AI, Mia AJ, Yorio T (1998). "Aquaporins (water channels): role in vasopressin-activated water transport". Proc. Soc. Exp. Biol. Med. 219 (3): 183–99. doi:10.3181/00379727-219-44332. PMID 9824541. 
  5. ^ Roudier N, Ripoche P, Gane P, Le Pennec PY, Daniels G, Cartron JP, Bailly P (2002). "AQP3 deficiency in humans and the molecular basis of a novel blood group system, GIL". J. Biol. Chem. 277 (48): 45854–9. doi:10.1074/jbc.M208999200. PMID 12239222. 

Further reading[edit]

External links[edit]