Arabinose isomerase

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arabinose isomerase
EC number5.3.1.3
CAS number9023-81-8
IntEnzIntEnz view
ExPASyNiceZyme view
MetaCycmetabolic pathway
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, an arabinose isomerase (EC is an enzyme that catalyzes the chemical reaction

D-arabinose D-ribulose

Hence, this enzyme has one substrate, D-arabinose, and one product, D-ribulose.

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is D-arabinose aldose-ketose-isomerase. Other names in common use include D-arabinose(L-fucose) isomerase, D-arabinose isomerase, L-fucose isomerase, and D-arabinose ketol-isomerase.

Structural studies[edit]

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1FUI.


  • Cohen SS (1953). "Studies on D-ribulose and its enzymatic conversion to D-arabinose". J. Biol. Chem. 201 (1): 71–84. PMID 13044776.
  • Green M, Cohen SS (1956). "Enzymatic conversion of L-fucose to L-fuculose". J. Biol. Chem. 219 (2): 557–568. PMID 13319278.