Highway 284 starts in Forrest City at an intersection with Highway 1B, as Newcastle Road in St. Francis County. It junctions with I-40 at exit 242. It junctions with Highway 306 near Colt a few miles north before crossing the county line. It enters Cross County from the South before joining US 64B and forming a concurrency. When US 64B ends, Highway 284 runs south for less than a quarter of a mile along Highway 1 before continuing westward. After leaving Wynne, the highway intersects Highway 350 and the two run concurrently together southbound before separating. Highway 284 then continues westward to a junction with Highway 193 and those two highways run concurrently southbound together for about one mile (1.6 km). Highway 284 once again return to an westward direction. The highway intersects the northern end of Highway 259 before terminating at US 49 near the Woodruff County line.