Arnold J. Levine

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Arnold J. Levine
Born July 30, 1939 (1939-07-30) (age 78)
Brooklyn, New York
Nationality American
Fields Molecular biology/Molecular virology/Molecular genetics
Alma mater Binghamton University
University of Pennsylvania
California Institute of Technology
Doctoral advisor Harold S. Ginsberg
Known for p53 tumor suppressor protein
Notable awards Ciba-Drew Award (1995)
Louisa Gross Horwitz Prize for Biology or Biochemistry (1998)
Charles S. Mott Prize (1999)
Keio Medical Science Prize (2000)
Albany Medical Center Prize in Medicine and Biomedical Research (2001)

Arnold J. Levine (born 1939), is an American Molecular biologist. He was awarded the 1998 Louisa Gross Horwitz Prize for Biology or Biochemistry and was the first recipient of the Albany Medical Center Prize in Medicine and Biomedical Research in 2001 for his discovery of the tumor suppressor protein p53.[1]

He is currently Professor of Systems Biology at the Institute for Advanced Study in Princeton New Jersey.[2]


Levine discovered, with several colleagues, the p53 tumor suppressor gene in 1979, a protein involved in cell cycle regulation, and one of the most frequently mutated genes in human cancer, in work done as a professor in the biochemistry department at Princeton University. In 1979 Levine moved to become Chairman of the Department of Microbiology at Stony Brook School of Medicine before moving back to Princeton in 1984.

In 1998 Levine became the Robert and Harriet Heilbrunn Professor of Cancer Biology and President of Rockefeller University. While he was President of Rockefeller University, he opted to resign due to allegations that he had an inappropriate sexual encounter with a woman graduate student, under intoxication. According to the involved woman student, the encounter was consensual.[3]

In 2002 he moved to the Robert Wood Johnson Medical School and in 2004 added a joint appointment as Professor at the Institute for Advanced Study.

Award and honors[edit]

In addition to the Louisa Gross Horwitz Prize (Columbia University) and Albany Prize Levine has received numerous awards and honors. He was elected a Member of the U.S. National Academy of Sciences in 1991,[4] and a Member of the Institute of Medicine in 1995.[5] He won the Ciba-Drew Award in 1995. The importance of p53 in cancer biology led to a number of cancer-related awards, including the Bristol-Myers Squibb Award for Distinguished Achievement in Cancer Research (1994), the Charles S. Mott Prize from the General Motors Cancer Research Foundation (1999), the Keio Medical Science Prize (2000).[6]

See also[edit]


  1. ^ Altman, Lawrence K. (March 15, 2001), "Scientist Wins Prize for Work on Cancer Gene", New York Times .
  2. ^ Faculty profile, Institute for Advanced Study, retrieved 2011-05-12.
  3. ^ Arenson, Karen W. (February 11, 2002), "Amid Inquiry, President of Rockefeller U. Resigns", New York Times. .
  4. ^ "NAS Membership Directory". U.S. National Academy of Sciences. Retrieved December 4, 2011.  Search for Arnold Levine.
  5. ^ "IOM Membership Directory - Arnold Levine". Institute of Medicine. Retrieved December 4, 2011. [permanent dead link]
  6. ^ "The Keio Medical Science Prize Laureates". Keio University. Retrieved December 4, 2011. 

External links[edit]