Artesunate/mefloquine

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Artesunate/mefloquine
Combination of
Artesunateartemisinin
Mefloquineantimalarial
Clinical data
ATC code

Artesunate/mefloquine is a medication used to treat malaria.[1] It is a fixed dose combination of artesunate and mefloquine.[1] Specifically it is recommended to treat uncomplicated falciparum malaria.[2] It is taken by mouth.[1]

Side effects are similar to the medications being used separately.[2] Use is recommended as it decreases the possibility of either medications being used alone.[2] Dose forms appropriate for children are also available.[2]

Artesunate/mefloquine came into commercial use in 2008.[3] It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.[1] It is approved for medical use in Brazil, India, and Malaysia.[2] In 2012 a course of treatment cost 2.50 USD.[3] It is not commercially available in the United States.[4]

Medical uses[edit]

Artesunate/mefloquine is a recommended treatment in Southeast Asia while in Africa artesunate/amodiaquine, artemether/lumefantrine, artesunate/sulfadoxine/pyrimethamine are often preferred.[5]

See also[edit]

References[edit]

  1. ^ a b c d "WHO Model List of Essential Medicines (19th List)" (PDF). World Health Organization. April 2015. Archived (PDF) from the original on 13 December 2016. Retrieved 8 December 2016.
  2. ^ a b c d e Organization, World Health (2014). The Selection and Use of Essential Medicines: Report of the WHO Expert Committee, 2013 (including the 18th WHO Model List of Essential Medicines and the 4th WHO Model List of Essential Medicines for Children). World Health Organization. p. 43. ISBN 9789241209854. Archived from the original on 2016-12-20.
  3. ^ a b Staines, Henry M.; Krishna, Sanjeev (2012). Treatment and Prevention of Malaria: Antimalarial Drug Chemistry, Action and Use. Springer Science & Business Media. p. 239. ISBN 9783034604802. Archived from the original on 2016-12-20.
  4. ^ Sanford, Christopher A.; Jong, Elaine C.; Pottinger, Paul S. (2016). The Travel and Tropical Medicine Manual (5 ed.). Elsevier Health Sciences. p. 307. ISBN 9780323417426. Archived from the original on 2016-12-20.
  5. ^ Marcondes, Carlos Brisola (2016). Arthropod Borne Diseases. Springer. p. 35. ISBN 9783319138848. Archived from the original on 2016-12-20.