There is controversy about what they are composed of. Traditionally, they were thought to be cytoskeletal elements and to consist primarily of vimentin. However, more recent research suggested that that was incorrect and that they may be composed of lipids arranged into bilayer membranes.
^Cain, H; Kraus, B (Dec 1977). "Asteroid bodies: derivatives of the cytosphere. An electron microscopic contribution to the pathology of the cytocentre.". Virchows Arch B Cell Pathol. 26 (2): 119–32. PMID204105.
^Cain, H; Kraus, B (1983). "Immunofluorescence microscopic demonstration of vimentin filaments in asteroid bodies of sarcoidosis. A comparison with electron microscopic findings.". Virchows Arch B Cell Pathol Incl Mol Pathol. 42 (2): 213–26. PMID6133393.
^Papadimitriou, JC; Drachenberg, CB (1992). "Ultrastructural analysis of asteroid bodies: Evidence for membrane lipid bilayer nature of components". Ultrastruct Pathol. 16 (4): 413–421. doi:10.3109/01913129209057826. PMID1323892.
^Kirkpatrick, CJ; Curry, A; Bisset, DL (1988). "Light- and electron-microscopic studies on multinucleated giant cells in sarcoid granuloma: new aspects of asteroid and Schaumann bodies.". Ultrastruct Pathol. 12 (6): 581–97. doi:10.3109/01913128809056483. PMID2853474.