Atlas of UTR Regulatory Activity
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|Description||Atlas of UTR Regulatory Activity|
|Research center||CIBIO - University of Trento|
|Laboratory||Laboratory of Translational Genomics|
|Authors||Erik Dassi, Andrea Malossini, Angela Re, Tommaso Mazza, Toma Tebaldi, Luigi Caputi and Alessandro Quattrone|
The Atlas of UTR Regulatory Activity (AURA), now at its second version, is a manually curated and comprehensive catalog of human 5' and 3' untranslated sequences (UTR) and UTR regulatory annotations.
It includes basic annotation, phylogenetic conservation, binding sites for RNA-binding proteins and miRNA, cis-elements, RNA methylation and editing data, and more, for human and mouse. Through its intuitive web interface, it furthermore provides full access to a wealth of information that integrates RNA sequence and structure data, variation sites, gene synteny, gene and protein expression and gene functional descriptions from scientific literature and specialized databases. Eventually, it provides several tool for batch analysis of gene lists, allowing the tracing of post-transcriptional regulatory networks.
- RNA-binding protein
- Untranslated region
- Five prime untranslated region
- Three prime untranslated region
- Dassi, E; Malossini A; Re A; Mazza T; Tebaldi T; Caputi L; Quattrone A (Jan 2012). "AURA: Atlas of UTR Regulatory Activity". Bioinformatics (England) 28 (1): 142–143. doi:10.1093/bioinformatics/btr608. PMID 22057158.
- Dassi, E; Re A; Leo S; Tebaldi T; Pasini L; Peroni D; Quattrone A (Jan 2014). "AURA 2: empowering discovery of post-transcriptional networks". Translation (England: Taylor&Francis) 2 (1). doi:10.4161/trla.27738.
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