Atypia (from Greek, a + typos, without type; a condition of being irregular or nonstandard) is a histopathologic term for a structural abnormality in a cell, i.e. it is used to describe atypical cells.
Examples for Barretts esophagus
- Nuclear stratification, wherein cell nuclei, which are normally located nearly at the same level between adjacent cells, are instead located at different levels.
- Prominent nucleoli
For example, already differentiated, specialised cells such as epithelia displaying "cellular atypia" are far less likely to become problematic [cancerous/ malignant] than are myeloid progenitor cells of the immune system. The 'further back' in an already specialised, differentiated cell's lineage, the more problematic cellular atypia is likely to be. This is due to the conferring of such atypia to progeny-cells further down the lineage of that cell type.
|Look up atypia in Wiktionary, the free dictionary.|
- Mosby's Medical Dictionary (8th edition). Elsevier.
- "dysplasia" at Dorland's Medical Dictionary
- "Definition and Characteristics of Dysplasia in Barrett's Esophagus". University of Washington. Retrieved 2019-09-27.