Atypical fibroxanthoma

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Atypical fibroxanthoma
Classification and external resources
Specialty oncology, rheumatology
ICD-10 C49 (ILDS C49.M12)

Atypical fibroxanthoma of the skin is a low-grade malignancy related to malignant fibrous histiocytoma, which it resembles histologically.[1]:613


It occurs most commonly on the skin of sun-exposed, elderly patients. The majority of tumors are on the scalp, face, ears and upper limbs, but less commonly the tumor occurs on the limbs and trunk when there is a lack of association with sun exposure in younger individuals. The condition has also been noted in organ transplant recipients who may be in a state of immunosuppression. It has been reported that there is a predominance in men (70% men versus 30% women).[2]

Differential diagnoses:


Surgical excision with clear margins.

See also[edit]


  1. ^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
  2. ^ Sakamoto, Akio (2008). "Atypical Fibroxanthoma". Clin Med Oncol. 2: 117–127. PMC 3161641Freely accessible. Text copied under the terms of the CC-by license, see source.