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AutoPulse on a Dummy

The AutoPulse is an automated, portable, battery-powered cardiopulmonary resuscitation device created by Revivant and subsequently purchased and currently manufactured by ZOLL Medical Corporation. It is a chest compression device composed of a constricting band and half backboard that is intended to be used as an adjunct to CPR during advanced cardiac life support by professional health care providers. The AutoPulse uses a distributing band to deliver the chest compressions. In literature it is also known as LDB-CPR (Load Distributing Band-CPR).

The AutoPulse measures chest size and resistance before it delivers the unique combination of thoracic and cardiac chest compressions. The compression depth and force varies per patient. The chest displacement equals a 20% reduction in the anterior-posterior chest depth. The physiological duty cycle is 50%, and it runs in a 30:2, 15:2 or continuous compression mode, which is user-selectable, at a rate of 80 compressions-per-minute.

Device operation[edit]

The patient's head, shoulders and upper back lay upon the base unit, with the controls for the AutoPulse beside the patient's left ear. It can be augmented for cervical spinal support. The unit contains the control computer, the rechargeable battery, and the motors that operate the LifeBand. The LifeBand is an adjustable strap that covers the entire rib cage. When the patient is strapped in and the start button is pressed, the LifeBand pulls tight around the chest, determines the patient's chest size and resistance, and proceeds to rhythmically constrict the entire rib cage, pumping the heart at a rate of 80 compressions per minute. The LifeBand can be placed over defibrillation pads. The LifeBand is disposable, and designed to be used on a single patient for sanitary reasons.

Mechanism of CPR blood flow[edit]

The load-distributing band system, employing thoracic compressions, produces higher blood flow compared to CPR consisting of sternal compressions only. The potential to produce blood flow for a sudden cardiac arrest victim is in large part determined by the peak power of the compression. Factors determining the power of the compression are the force of the compression, the depth of the compression, and the duration that the compression is held at maximum depth.

Cardiac Pump
Cardiac Pump - Compresses mainly the heart
Thoracic Pump
Thoracic Pump - Compresses the entire chest
Thoracic and Cardiac Pump combined
Thoracic and Cardiac Pump combined

Studies and clinical trials[edit]

The gold standard for resuscitation research is survival to hospital discharge. Although common sense suggests that short-term and intermediate outcomes like return of spontaneous circulation (ROSC) or survival to hospital admission are promising, experienced scientists know that anything less than a neurologically intact survivor walking out of the hospital is ultimately irrelevant.[1]

Several animal studies have shown that automated CPR machines are more effective at providing circulatory support than manual CPR. One study showed that use of the AutoPulse produced blood flow to the heart and brain that was comparable to pre-arrest levels.[2] In another study, an adapted AutoPulse was shown to be highly effective in support of cardiac arrest in animals, whereas manual CPR was tenuous in its effectiveness. Pigs were used in the study, and were left in cardiac arrest for eight minutes to simulate average ambulance response time. 73% of the pigs that were put into the AutoPulse were revived, and 88% of the surviving pigs showed no neurological damage. None of the pigs that received manual CPR survived.[3]

The Circulation Improving Resuscitation Care (CIRC) trial is the largest prospective randomized trial to date for mechanical chest compressions in out-of-hospital cardiac arrest (OHCA). The goal was to demonstrate that the AutoPulse Non-invasive Cardiac Support Pump is a safe and effective component of a system of care focusing on high-quality chest compressions.

Compared to high-quality manual CPR, AutoPulse CPR resulted in statistically equivalent survival to hospital discharge and no difference in neurologic status at discharge in adults with out-of-hospital cardiac arrest of presumed cardiac etiology.[4]

There are times when delivering high quality manual CPR isn’t practical or even possible; the results of the CIRC trial confirm the important role the AutoPulse system can play in improving resuscitation outcomes.

The American Heart Association Guidelines for Cardiopulmonary Resuscitation give load-distributing band CPR (LDB-CPR) a Class IIb recommendation.[5]

Class I Definitely recommended. Supported by excellent evidence.
Class IIa Acceptable and useful. Good to very good evidence provides support.
Class IIb Acceptable and useful. Fair to good evidence provides support.
Class III Unacceptable, no documented benefit, may be harmful.

In the news[edit]

Mirror, a U.K. news website, on January 14, 2011, reports on Arun Bhasin, who 'came back from the dead' after 3 and a half hours. He was found unconscious and brought into Croydon University Hospital. He suffered a cardiac arrest and was placed on the AutoPulse, which performed almost 20,000 compressions, keeping his heart and lungs functioning while a medical team worked on him. After almost 3 and a half hours, his pulse returned.[6]

CNN's Anderson Cooper 360° featured a story on April 6, 2010, about the Firehouse Subs Public Safety Foundation, in which Firehouse Subs founders Chris and Robin Sorensen met with Francisco Tuttle, a father who was saved by the Mt. Pleasant, SC, Fire Department using a ZOLL AutoPulse, which the Foundation donated to the department last year.[citation needed]

ABC World News Tonight on September 22, 2004, did a story on automated CPR machines, and profiled the story of Caralee Weich, who survived thirty-five minutes of cardiac arrest during which the AutoPulse was used. She had a Sudden Cardiac Arrest in front of a theatre. Two nurses began immediate CPR. After a half-hour with no heartbeat, she ultimately recovered with no apparent brain damage.MEDICINE ON THE CUTTING EDGE BETTER CPR (tape). ABC News. 2004. 


The AutoPulse has received a fair amount of criticism surrounding its battery life, bulk, and studies suggesting poor survival to hospital discharge. The most notable case of such issues can be found in the news reports of the resuscitation of Prince Friso after he and his companion were caught in an avalanche. In that case, the AutoPulse batteries failed after only 9 and 15 minutes.[7] Others have criticized the high cost and non-reimbursable nature of the disposable AutoPulse LifeBand.

The new AutoPulse Power System is based on intelligent technology that is designed to simplify maintenance of AutoPulse batteries by automating monthly conditioning. The AutoPulse can be operated with Li-Ion (lithium-ion) batteries which are designed for busy, mobile environments where weight is an overriding concern.

Studies have also failed to show an increase in survival to hospital discharge. During the ASPIRE trial (the first multi-centered, randomized trial with large enrollment), the survival to hospital discharge rates decreased from 9.9% with manual CPR to approximately 5%. Because of these findings, the ethics review board terminated the study. However, some researchers question the validity of the ASPIRE protocol.[8] The CIRC study results additionally indicate that the AutoPulse increases the time before first defibrillation and decrease the average compressions per minute in comparison with manual CPR. Overall, the study shows no improvement over high quality manual CPR.[9]

Several cases have been reported where the AutoPulse has caused additional injury to patients receiving compressions from the device.[10][11]

Some departments and agencies have begun discontinuing the use of the AutoPulse, citing battery and reliability issues.[12]


  1. ^ ACLS: Principles and Practice. Dallas: American Heart Association. 2003. p. 62. ISBN 0-87493-341-2. 
  2. ^ Halperin, Henry R.; Paradis, Norman; Ornato, Joseph P.; Zviman, Menekhem; Lacorte, Jennifer; Lardo, Albert; Kern, Karl B. (2004). "Cardiopulmonary resuscitation with a novel chest compression device in a porcine model of cardiac arrest". Journal of the American College of Cardiology. 44 (11): 2214–20. doi:10.1016/j.jacc.2004.08.061. PMID 15582320. 
  3. ^ Ikeno, Fumiaki; Lyons, Jennifer; Kaneda, Hideaki; Hongo, Yoichiro; Emami, Sascha; Nolasco, Christine; Rezaee, Mehrdad (2004). "1154-95 Chest compression device improves blood flow in cerebrum and myocardium achieving neurologically intact survival in a porcine model of prolonged cardiac arrest". Journal of the American College of Cardiology. 43 (5): A301. doi:10.1016/S0735-1097(04)91275-2. 
  4. ^ Wik L, Olsen JA, Persse D, Sterz F, Lozano M Jr, Brouwer MA, Westfall M, Souders CM, Malzer R, van Grunsven PM, Travis DT, Whitehead A, Herken UR, Lerner EB (2014). "Manual vs. integrated automatic load-distributing band CPR with equal survival after out of hospital cardiac arrest. The randomized CIRC trial.". Resuscitation. 85 (6): 741–8. doi:10.1016/j.resuscitation.2014.03.005. PMID 24642406. 
  5. ^ "Part 6: CPR Techniques and Devices". Circulation. 112 (24_suppl): IV–47. 2005. doi:10.1161/CIRCULATIONAHA.105.166555. 
  6. ^ "Miracle man comes back 'from the dead' after 3.5 hours - medical skill and high tec machine save him". Daily Mirror. 2011-01-14. Archived from the original on 2012-02-13. Retrieved 2013-02-07. 
  7. ^[full citation needed]
  8. ^ Paradis, Norman A.; Young, Gregory; Lemeshow, Stanley; Brewer, James E.; Halperin, Henry R. (2010). "Inhomogeneity and temporal effects in AutoPulse Assisted Prehospital International Resuscitation—an exception from consent trial terminated early". The American Journal of Emergency Medicine. 28 (4): 391–8. doi:10.1016/j.ajem.2010.02.002. PMID 20466215. 
  9. ^[full citation needed]
  10. ^ Wind, J.; Bekkers, S.C.A.M.; Van Hooren, L.J.H.; Van Heurn, L.W.E. (2009). "Extensive injury after use of a mechanical cardiopulmonary resuscitation device". The American Journal of Emergency Medicine. 27 (8): 1017.e1. doi:10.1016/j.ajem.2008.11.018. 
  11. ^ Hart, AP; Azar, VJ; Hart, KR; Stephens, BG (2005). "Autopsy artifact created by the Revivant AutoPulse resuscitation device". Journal of forensic sciences. 50 (1): 164–8. doi:10.1520/jfs2004155. PMID 15831013. 
  12. ^

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