Autologous stem-cell transplantation
Autologous stem-cell transplantation (also called autogenous, autogeneic, or autogenic stem-cell transplantation and abbreviated auto-SCT) is autologous transplantation of stem cells—that is, transplantation in which stem cells (undifferentiated cells from which other cell types develop) are removed from a person, stored, and later given back to that same person.
Although it is most frequently performed with hematopoietic stem cells (precursors of blood-forming cells) in hematopoietic stem cell transplantation, cardiac cells have also been used successfully to repair damage caused by heart attacks.
Autologous stem-cell transplantation is distinguished from allogenic stem cell transplantation where the donor and the recipient of the stem cells are different people.
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- Stamm, Christof; Westphal, Bernd; Kleine, Hans-Dieter; Petzsch, Michael; Kittner, Christian; Klinge, Heiko; Schümichen, Carl; Nienaber, Christoph A; Freund, Mathias (2003-01-04). "Autologous bone-marrow stem-cell transplantation for myocardial regeneration". The Lancet. 361 (9351): 45–46. doi:10.1016/S0140-6736(03)12110-1.
- This article incorporates public domain material from the U.S. National Cancer Institute document "Dictionary of Cancer Terms".
- Autologous stem-cell transplantation entry in the public domain NCI Dictionary of Cancer Terms
- ScienceDaily Report University of Louisville. "Two years out, patients receiving stem cell therapy show sustained heart function improvement, study suggests." ScienceDaily, 6 Nov. 2012. Web. 6 Nov. 2012.
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