Autologous stem-cell transplantation

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Autologous stem-cell transplantation (also called autogenous, autogeneic, or autogenic stem-cell transplantation and abbreviated auto-SCT) is autologous transplantation of stem cells[1]—that is, transplantation in which stem cells (undifferentiated cells from which other cell types develop) are removed from a person, stored, and later given back to that same person.[2][3]

Although it is most frequently performed with hematopoietic stem cells (precursors of blood-forming cells) in hematopoietic stem cell transplantation, cardiac cells have also been used successfully to repair damage caused by heart attacks.[4]

Autologous stem-cell transplantation is distinguished from allogenic stem cell transplantation where the donor and the recipient of the stem cells are different people.

See also[edit]

References[edit]

  1. ^ "What Are Stem Cells?". Retrieved 2017-02-12.
  2. ^ Mahla RS (2016). "Stem cells application in regenerative medicine and disease threpeutics". International Journal of Cell Biology. 2016 (7): 19. doi:10.1155/2016/6940283. PMID 27516776.
  3. ^ "Autologous (Self) Transplants". The Leukaemia Foundation. The Leukaemia Foundation. Retrieved 27 September 2017.
  4. ^ Stamm, Christof; Westphal, Bernd; Kleine, Hans-Dieter; Petzsch, Michael; Kittner, Christian; Klinge, Heiko; Schümichen, Carl; Nienaber, Christoph A; Freund, Mathias (2003-01-04). "Autologous bone-marrow stem-cell transplantation for myocardial regeneration". The Lancet. 361 (9351): 45–46. doi:10.1016/S0140-6736(03)12110-1.

External links[edit]

  • Autologous stem-cell transplantation entry in the public domain NCI Dictionary of Cancer Terms
  • ScienceDaily Report University of Louisville. "Two years out, patients receiving stem cell therapy show sustained heart function improvement, study suggests." ScienceDaily, 6 Nov. 2012. Web. 6 Nov. 2012.