|Description||Protein involved in autophagy|
|Research center||Center for Information Biology and DNA Data Bank of Japan|
|Primary citation||Homma & al.|
The Autophagy database is a database of proteins involved in autophagy, a catabolic process involving the degradation of a cell's own components through the lysosomal machinery. Its molecular mechanisms have not been fully elucidated, despite dramatic advances in the field as evidenced by hundreds of autophagy-related genes and proteins reported. The Autophagy database intends to collect all relevant information, organize it, and make it publicly available so that its users can easily get up-to-date knowledge.
Specifically, the database aims to make a comprehensive list of autophagy-related genes and proteins, identifies orthologs and other homologs, adds many kinds of information including sequences, functions, 3D structures, and makes them accessible in a searchable format. It also provides recently published references on autophagy with user ratings, a list of informative reviews, and results of an original analysis. The database was made publicly available in March 2010 and was updated to include 7,444 genes/proteins in 82 eukaryotes.
- Homma, Keiichi; Suzuki Koji; Sugawara Hideaki (Jan 2011). "The Autophagy Database: an all-inclusive information resource on autophagy that provides nourishment for research". Nucleic Acids Res. England. 39 (Database issue): D986–90. doi:10.1093/nar/gkq995. PMC . PMID 20972215.
- Another database specializing in human autophagy (http://autophagy.lu/) is also publicly available.