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Virus classification
Group: Group VII (dsDNA-RT)
Family: Hepadnaviridae
Genus: Avihepadnavirus
Type Species

Avihepadnavirus is a genus of viruses, in the family Hepadnaviridae. Birds serve as natural hosts. There are currently only two species in this genus including the type species Duck hepatitis B virus. Diseases associated with this genus include: hepatitis, hepatocellular carcinomas (chronic infections), cirrhosis.[1][2][3]


Group: ssRNA-RT



Viruses in Avihepadnavirus are enveloped, with spherical geometries, and T=4 symmetry. The diameter is around 42 nm. Genomes are circular, around 3.2kb in length. The genome codes for 7 proteins.[1]

Genus Structure Symmetry Capsid Genomic Arrangement Genomic Segmentation
Avihepadnavirus Icosahedral T=4 Non-Enveloped Circular Monopartite

Life Cycle[edit]

Viral replication is nucleo-cytoplasmic. Replication follows the dsDNA(RT) replication model. Dna templated transcription, specifically dsdna(rt) transcription, with some alternative splicing mechanism is the method of transcription. Translation takes place by ribosomal shunting. The virus exits the host cell by budding, and nuclear pore export. Birds serve as the natural host. Transmission routes are parental, sexual, and blood.[1]

Genus Host Details Tissue Tropism Entry Details Release Details Replication Site Assembly Site Transmission
Avihepadnavirus Birds Hepatocytes Cell receptor endocytosis Budding Nucleus Cytoplasm Vertical: parental; sex; blood


  1. ^ a b c "Viral Zone". ExPASy. Retrieved 12 June 2015. 
  2. ^ a b ICTV. "Virus Taxonomy: 2014 Release". Retrieved 12 June 2015. 
  3. ^ Guo, Haitao; Mason, William (2005). "Identification and Characterization of Avihepadnaviruses Isolated from Exotic Anseriformes Maintained in Captivity". Journal of Virology. American Society for Microbiology. 79 (5): 2729–2742. doi:10.1128/JVI.79.5.2729-2742.2005. PMC 548436free to read. PMID 15708992. Retrieved 10 March 2012. 

External links[edit]