Azalanstat

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Azalanstat
Azalanstat.svg
Clinical data
ATC code
  • None
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC22H24ClN3O2S
Molar mass429.963 g/mol g·mol−1
3D model (JSmol)
 ☒N☑Y (what is this?)

Azalanstat (INN,[1] codenamed RS-21607) is an anti-obesity drug acting as a lanosterol 14α-demethylase inhibitor.[2][3]

References[edit]

  1. ^ "International Nonproprietary Names for Pharmaceutical Substances (INN). Recommended International Nonproprietary Names (Rec. INN): List 36" (PDF). World Health Organization. p. 141. Retrieved 3 January 2017.
  2. ^ Walker, KA; Kertesz, DJ; Rotstein, DM; Swinney, DC; Berry, PW; So, OY; Webb, AS; Watson, DM; Mak, AY; Burton, PM (23 July 1993). "Selective Inhibition of Mammalian Lanosterol 14α-Demethylase: A Possible Strategy for Cholesterol Lowering". Journal of Medicinal Chemistry. 36 (15): 2235–7. doi:10.1021/jm00067a022. PMID 8340925.
  3. ^ Burton, PM; Swinney, DC; Heller, R; Dunlap, B; Chiou, M; Malonzo, E; Haller, J; Walker, KA; Salari, A; Murakami, S (8 August 1995). "Azalanstat (RS-21607), a Lanosterol 14α-Demethylase Inhibitor with Cholesterol-Lowering Activity". Biochemical Pharmacology. 50 (4): 529–44. doi:10.1016/0006-2952(95)00152-p. PMID 7646560.