Azilone-Ampaza is located in the Panicale Valley in the Middle Taravo region some 22 km east by south-east of Ajaccio and 4 km east of Grosseto-Prugna. The D83 road from Santa-Maria-Siché to Zévaco passes through the northern tip of the commune but has no connection to the village. Access to the village is by road D26 from Olivese in the south-east which enters the commune from the south, passing through the village, then loops south again to join the Route nationale N196 south-west of the commune. Apart from the main village there are the hamlets of Ampaza in the north-west and Azilone south of the village. The commune is rugged and heavily forested.
Both villages originated from the hamlet of Calcinaghju which was in the middle of the valley and destroyed by the Moors. Under the Paolinu and Genovese administrative systems, the commune belonged to the Pieve of Ornano. The town is now mainly known for being a high point on the Tour de Corse, an event that counts for the World Rally Championship (WRC).
In 2010 the commune had 142 inhabitants. The evolution of the number of inhabitants is known from the population censuses conducted in the commune since 1793. From the 21st century, a census of communes with fewer than 10,000 inhabitants is held every five years, unlike larger communes that have a sample survey every year.[Note 1]
^At the beginning of the 21st century, the methods of identification have been modified by Law No. 2002-276 of 27 February 2002, the so-called "law of local democracy" and in particular Title V "census operations" allows, after a transitional period running from 2004 to 2008, the annual publication of the legal population of the different French administrative districts. For communes with a population greater than 10,000 inhabitants, a sample survey is conducted annually, the entire territory of these communes is taken into account at the end of the period of five years. The first "legal population" after 1999 under this new law came into force on 1 January 2009 and was based on the census of 2006.