Azoximer bromide

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Azoximer bromide
Azoximer bromide.svg
Systematic (IUPAC) name
Poly[[1-(carboxymethyl)piperazin-1-ium-1,4-diyl bromide]ethylene- co-[(piperazin-1,4-diyl 1-oxide)ethylene]]
Pharmacokinetic data
Bioavailability up to 89%
Biological half-life 25.4 hours (intravenous routes)
CAS Registry Number 892497-01-7
ATC code L03AX
Synonyms Polyoxidonium, Synpol
Chemical data
Formula [[C8H15BrN2O2]x[C6H12N2O]y]n
Molecular mass 60000–100000 g/mol

Azoximer bromide is a macromolecular compound with high-molecular weight and high immunomodulating activity. It is used in Russia and CIS in treatment and prophylaxis of diseases connected with damage of immune system. It is a N-oxidized polyethylene–piperazine derivative.

Azoximer bromide is registered in US Patent-5503830 from 1996,[1][2][3] in the Russian Federation from 1996, under registration number 96/302/9, FS 42-3906-00.[4]


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  4. ^ State Scientific Centre of Russian federation, Immunological Institute of Russian Federation Health Resort, CLINICAL ASPECTS OF USE OF IMMUNOMODULATOR POLYOXIDONIUM, Methodical handbook for doctors issued by State Scientific Centre of Russian Federation – Immunological Institute of Russian Federation Health Resort Moscow – 2003