Bützow is a town in the district of Rostock in Mecklenburg-Vorpommern, Germany.
The town was first mentioned in 1171. From 1815 to 1918 Bützow was part of the Grand Duchy of Mecklenburg-Schwerin.
On 5 May 2015, the town was struck by an F3 tornado which caused severe damage to many buildings, including the local hospital.
Medieval Bützow Castle is located in Bützow. The town also has a medieval Brick Gothic church, which contains an altarpiece made by the Master of the Bützow Altarpiece (1503).