B3GAT3

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B3GAT3
Protein B3GAT3 PDB 1fgg.png
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesB3GAT3, GLCATI, glcUAT-I, JDSCD, beta-1,3-glucuronyltransferase 3
External IDsMGI: 1919977 HomoloGene: 56554 GeneCards: B3GAT3
Gene location (Human)
Chromosome 11 (human)
Chr.Chromosome 11 (human)[1]
Chromosome 11 (human)
Genomic location for B3GAT3
Genomic location for B3GAT3
Band11q12.3Start62,615,296 bp[1]
End62,622,154 bp[1]
RNA expression pattern
PBB GE B3GAT3 35179 at fs.png

PBB GE B3GAT3 203452 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001288721
NM_001288722
NM_001288723
NM_012200

NM_024256

RefSeq (protein)

NP_001275650
NP_001275651
NP_001275652
NP_036332

NP_077218

Location (UCSC)Chr 11: 62.62 – 62.62 MbChr 19: 8.92 – 8.93 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 is an enzyme that in humans is encoded by the B3GAT3 gene.[5][6]

The protein encoded by this gene is a member of the glucuronyltransferase gene family, enzymes that exhibit strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric linkages. This gene product catalyzes the formation of the glycosaminoglycan-protein linkage by way of a glucuronyl transfer reaction in the final step of the biosynthesis of the linkage region of proteoglycans.[6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000149541 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000071649 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Kitagawa H, Tone Y, Tamura J, Neumann KW, Ogawa T, Oka S, Kawasaki T, Sugahara K (Apr 1998). "Molecular cloning and expression of glucuronyltransferase I involved in the biosynthesis of the glycosaminoglycan-protein linkage region of proteoglycans". J Biol Chem. 273 (12): 6615–8. doi:10.1074/jbc.273.12.6615. PMID 9506957.
  6. ^ a b "Entrez Gene: B3GAT3 beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)".

External links[edit]

Further reading[edit]