BFSP1

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BFSP1
Identifiers
Aliases BFSP1, CP115, CP94, CTRCT33, LIFL-H, beaded filament structural protein 1
External IDs MGI: 101770 HomoloGene: 922 GeneCards: 631
RNA expression pattern
PBB GE BFSP1 206746 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001161705
NM_001195
NM_001278606
NM_001278607
NM_001278608

NM_001291061
NM_009751

RefSeq (protein)

NP_001155177.1
NP_001186.1
NP_001265535.1
NP_001265536.1
NP_001265537.1

NP_001277990.1
NP_033881.2

Location (UCSC) Chr 20: 17.49 – 17.57 Mb Chr 2: 143.83 – 143.86 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

BFSP1 is a gene that encodes the protein filensin in humans.[1][2]

More than 99% of the vertebrate ocular lens is made up of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (also known as phakinin) and the protein product of this gene, filensin (or CP115), are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF).[2]

References[edit]

  1. ^ Rendtorff ND, Hansen C, Silahtaroglu A, Henriksen KF, Tommerup N (Dec 1998). "Isolation of the human beaded-filament structural protein 1 gene (BFSP1) and assignment to chromosome 20p11.23-p12.1". Genomics 53 (1): 114–6. doi:10.1006/geno.1998.5478. PMID 9787085. 
  2. ^ a b "Entrez Gene: BFSP1 beaded filament structural protein 1, filensin". 

Further reading[edit]