BMY-7378

From Wikipedia, the free encyclopedia
  (Redirected from BMY-7,378)
Jump to navigation Jump to search
BMY-7378
Bmy-7378.svg
Identifiers
  • 8-(2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl)-8-azaspiro[4.5]decane-7,9-dione
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC22H31N3O3
Molar mass385.508 g·mol−1
3D model (JSmol)
  • C4CCCC4(CC1=O)CC(=O)N1CCN3CCN(CC3)c2ccccc2OC
  • InChI=1S/C22H31N3O3/c1-28-19-7-3-2-6-18(19)24-13-10-23(11-14-24)12-15-25-20(26)16-22(17-21(25)27)8-4-5-9-22/h2-3,6-7H,4-5,8-17H2,1H3 ☒N
  • Key:AYYCFGDXLUPJAQ-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

BMY-7,378 is a 5-HT1A receptor weak partial agonist/antagonist and α1D-adrenergic receptor antagonist.[1]

References[edit]

  1. ^ Goetz AS, King HK, Ward SD, True TA, Rimele TJ, Saussy DL (January 1995). "BMY 7378 is a selective antagonist of the D subtype of alpha 1-adrenoceptors". European Journal of Pharmacology. 272 (2–3): R5–6. doi:10.1016/0014-2999(94)00751-R. PMID 7713154.