BNR/Asp-box repeat

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BNR/Asp-box repeat
PDB 1euu EBI.jpg
Structure of a bacterial sialidase.[1]
Identifiers
Symbol BNR
Pfam PF02012
Pfam clan CL0434
InterPro IPR002860
SCOP 1euu
SUPERFAMILY 1euu

BNR/Asp-box repeat is a repetitive sequence of amino acids contained in some proteins.

Members of this family contain multiple BNR (bacterial neuraminidase repeat) repeats or Asp-boxes. The repeats are short, however the repeats are never found closer than 40 residues together suggesting that the repeat is structurally longer. These repeats are found in a variety of non-homologous proteins, including bacterial ribonucleases, sulphite oxidases, reelin, netrins, sialidases, neuraminidases, some lipoprotein receptors, and a variety of glycosyl hydrolases.[2]

Members of this family contain multiple BNR (bacterial neuraminidase repeat) repeats or Asp-boxes.


Examples[edit]

Human genes encoding proteins containing this domain include:

References[edit]

  1. ^ Gaskell, A; Crennell, S; Taylor, G (November 1995). "The three domains of a bacterial sialidase: a beta-propeller, an immunoglobulin module and a galactose-binding jelly-roll". Structure 3 (11): 1197–205. doi:10.1016/s0969-2126(01)00255-6. PMID 8591030. 
  2. ^ Ponting, CP; Russell, RB; Copley, RR (2001). "Sialidase-like Asp-boxes: sequence-similar structures within different protein folds". Protein Science 10 (2): 285–292. doi:10.1110/ps.31901. PMC 2373934. PMID 11266614. 

This article incorporates text from the public domain Pfam and InterPro IPR002860