BST1

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BST1
Protein BST1 PDB 1isf.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases BST1, CD157, bone marrow stromal cell antigen 1
External IDs MGI: 105370 HomoloGene: 3198 GeneCards: BST1
Genetically Related Diseases
Parkinson's disease[1]
RNA expression pattern
PBB GE BST1 205715 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004334

NM_009763

RefSeq (protein)

NP_004325

NP_033893.2
NP_033893

Location (UCSC) Chr 4: 15.7 – 15.74 Mb Chr 5: 43.82 – 43.84 Mb
PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

ADP-ribosyl cyclase 2 is an enzyme that in humans is encoded by the BST1 gene.[4][5]

Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population.[5]

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.