BST1

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BST1
Protein BST1 PDB 1isf.png
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesBST1, CD157, bone marrow stromal cell antigen 1
External IDsMGI: 105370 HomoloGene: 3198 GeneCards: BST1
Gene location (Human)
Chromosome 4 (human)
Chr.Chromosome 4 (human)[1]
Chromosome 4 (human)
Genomic location for BST1
Genomic location for BST1
Band4p15.32Start15,702,950 bp[1]
End15,738,313 bp[1]
RNA expression pattern
PBB GE BST1 205715 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004334

NM_009763

RefSeq (protein)

NP_004325

NP_033893

Location (UCSC)Chr 4: 15.7 – 15.74 MbChr 5: 43.82 – 43.84 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

ADP-ribosyl cyclase 2 is an enzyme that in humans is encoded by the BST1 gene.[5][6]

Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population.[6]

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.