BTAF1

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BTAF1
Identifiers
Aliases BTAF1, MOT1, TAF(II)170, TAF172, TAFII170, B-TFIID TATA-box binding protein associated factor 1
External IDs MGI: 2147538 HomoloGene: 31978 GeneCards: BTAF1
RNA expression pattern
PBB GE BTAF1 209430 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003972

NM_001080706

RefSeq (protein)

NP_003963
NP_003963.1

NP_001074175

Location (UCSC) Chr 10: 91.92 – 92.03 Mb Chr 19: 36.93 – 37.01 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

TATA-binding protein-associated factor 172 is a protein that in humans is encoded by the BTAF1 gene.[3][4][5]

Function[edit]

Initiation of transcription by RNA polymerase II requires the assistance of TATA box-binding protein (TBP; MIM 600075) and TBP-associated factors, or TAFs (e.g., TAF2B; MIM 604912), in 2 distinct complexes, TFIID and B-TFIID. The TFIID complex is composed of TBP and more than 8 TAFs. However, the majority of TBP is present in the B-TFIID complex, which is composed of TBP and TAFII170, also called TAF172, and has DNA-dependent ATPase activity.[supplied by OMIM][5]

Interactions[edit]

BTAF1 has been shown to interact with TATA binding protein.[4][6]

References[edit]

External links[edit]

Further reading[edit]