Topical antibiotics like metronidazole cream and antifungals clotrimazole cream or low-potency steroid creams are suggested beneficial for this disease.
Proper hygiene and regular washing of prepuce is useful for the prevention of balanoposthitis.
Circumcision may be promoted in recurrent and recalcitrant cases.
Since anaerobic conditions are necessary for growth of the offending organisms, simple exposure to air and local cleansing is most often effective. Formerly, this treatment, used with peroxide powder and arsphenamine and, in severe cases, a dorsal slit, was the extent of therapy. With the advent of penicillin and other systemic and local antibiotics, the treatment is specific and effective; however, even now a dorsal slit procedure is sometimes necessary.
^Rebecca Vaughan-Higgins, Nicky Buller, J. Anthony Friend, Ian Robertson, Cree L. Monaghan, Stan Fenwick, and Kristin Warren (2011) Balanoposthitis, Dyspareunia, and Treponema in the Critically Endangered Gilbert's Potoroo (Potorous gilbertii). Journal of Wildlife Diseases: October 2011, Vol. 47, No. 4, pp. 1019-1025.