Banti's syndrome (also known as Banti's disease) is a chronic congestive enlargement of the spleen resulting in premature destruction of the red blood cells by the spleen. It is named for Guido Banti.
The basic pathology is some kind of obstructive pathology in the portal, hepatic or splenic vein that causes obstruction of venous blood flow from the spleen towards the heart. The cause of such obstruction may be abnormalities present at birth (congenital) of certain veins, blood clots, or various underlying disorders causing inflammation and obstruction of veins (vascular obstruction) of the liver.
Enlargement of spleen, ascites, jaundice, and the result of destruction of various blood cells by spleen – anemia, leukopenia, thrombocytopenia, gastrointestinal bleeding – may constitute the presenting symptoms.
- WebMD article
- Free Dictionary article
- 1937 article in The Journal of Clinical Investigation[permanent dead link]
Organizations related to Banti's syndrome are: