Bartolomé de la Cueva y Toledo
Bartolomé de la Cueva y Toledo was born in Cuéllar on August 24, 1499, the son of Francisco Fernández de la Cueva, 2nd Duke of Alburquerque and his wife Francisca de Toledo.
As a young man, before he took Holy Orders, he had an illegitimate son, Bartolomé de la Cueva. Following his ordination, he was a cleric in the Diocese of Segovia, and a canon of the cathedral chapter of Toledo Cathedral. He also worked for the Apostolic See in Spain. In 1525, he and his brother Luis accompanied Charles V, Holy Roman Emperor during the emperor's visit to Italy.
Cardinal de la Cueva did not participate in the Council of Trent. He was a friend of Ignatius of Loyola, joining Loyola's Sociedad de la Gracia at Santa Marta al Collegio Romano in Rome in 1543. He was also the patron of the first Jesuit church build in Rome by Michelangelo in 1544.
Pope Paul III made him a cardinal priest in the consistory of December 19, 1544. He received the red hat and the titular church of San Matteo in Via Merulana on May 5, 1546. As a cardinal, he often resided at the papal court in Rome. Charles V was annoyed that Pedro Pacheco, Bishop of Pamplona was not elevated to the cardinalate and he forbade the three Spaniards made cardinals on December 19, 1544 from wearing the cardinalate habit until Bishop Pacheco was also made a cardinal the next year.
He participated in the papal conclave of 1549-50 that elected Pope Julius III. On December 4, 1551, he opted for the titular church of San Bartolomeo all'Isola. He served as Camerlengo of the Sacred College of Cardinals from January 12, 1554 to January 7, 1555. Cardinal de la Cueva participated in both the papal conclave of April 1555 that elected Pope Marcellus II and the papal conclave of May 1555 that elected Pope Paul IV. He opted for the titular church of Santa Croce in Gerusalemme on May 29, 1555.
He was a participant in the papal conclave of 1559 that elected Pope Pius IV. The new pope appointed him to a commission of cardinals tasked with studying church reform in 1560. On September 13, 1560, he was promoted to the metropolitan see of Manfredonia.
He died in the former Medici palace in Rome on June 29, 1562. He was initially buried in Nostra Signora del Sacro Cuore. His remains were later transferred to the family tomb in the monastery of San Francisco in Cuéllar.