(Regnery et al. 1992)
Bartonella henselae, formerly Rochalimæa, is a proteobacterium that can cause bacteremia, endocarditis, bacillary angiomatosis, and peliosis hepatis. It is also the causative agent of cat-scratch disease (bartonellosis) which, as the name suggests, occurs after a cat bite or scratch. The disease is characterized by lymphadenopathy (swelling of the lymph nodes) and fever.
Peliosis hepatis caused by B. henselae can occur alone or develop with cutaneous bacillary angiomatosis or bacteremia. Patients with peliosis hepatis present with gastrointestinal symptoms, fever, chills, and an enlarged liver and spleen containing blood-filled cavities. This systemic disease is mostly seen in patients infected with HIV and other immunocompromised individuals.
B. henselae is a Gram-negative rod. It can be cultured in a lysis-centrifugation blood culture. The diagnosis is made after a detailed patient history and physical is taken. A hallmark of the infectious process includes history of contact with a cat (hence the name cat scratch disease).
- Enlarged, tender lymph nodes that develop 1–3 weeks after exposure
- A papule or pustule at the inoculation site
- Jerris RC, Regnery RL (1996). "Will the real agent of cat-scratch disease please stand up?". Annu. Rev. Microbiol. 50: 707–25. PMID 8905096. doi:10.1146/annurev.micro.50.1.707.
- Kavita Diddi; Rama Chaudhry; Nidhi Sharma; Benu Dhawan (28 March 2011). "Strategy for identification & characterization of Bartonella henselae with conventional & molecular methods". Indian Journal of Medical Research. 137: 380–387. PMC .
- Bernard La Scola; Didier Raoult (17 March 1999). "Culture of Bartonella quintana and Bartonella henselae from Human Samples: a 5-Year Experience (1993 to 1998)" (PDF). Journal of Clinical Microbiology. 37 (6): 1899–1905. Retrieved 1 December 2016.
- "Bartonella Infection (Cat Scratch Disease, Trench Fever, and Carrión’s Disease)". Centers for Disease Control and Prevention. 29 November 2012.
- Bartonellosis~treatment at eMedicine
- "Bartonella henselae". NCBI Taxonomy Browser. 38323.
- Type strain of Bartonella henselae at BacDive - the Bacterial Diversity Metadatabase