Bartonella henselae

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Bartonella henselae
Blood culture negative endocarditis.jpg
Scientific classification
B. henselae
Binomial name
Bartonella henselae
(Regnery et al. 1992)

Bartonella henselae, formerly Rochalimæa, is a proteobacterium that is the causative agent of cat-scratch disease[1] (bartonellosis).

B. henselae is a member of the genus Bartonella, one of the most common types of bacteria in the world. It infects the host cell by sticking to it using trimeric autotransporter adhesins.[2]


B. henselae is a Gram-negative rod.[3][4] It can be cultured in a lysis-centrifugation blood culture.[5] The presence of bacteria can be detected by Warthin-Starry stain, or by a similar silver stain technique performed on infected tissue.

The specific name henselae honors Diane Marie Hensel (b. 1953), a clinical microbiology technologist at University of Oklahoma Health Sciences Center, who collected numerous strains and samples of the infective agent during an outbreak in Oklahoma in 1985.[6]

Bartonella henselae infection can appear up to ten days after exposure to the microbe. Symptoms start with a papule at the site the microbe enters, followed by lymphadenopathy, usually in the axillary node. Half of patients also get aches, nausea, abdominal pain, and malaise. [7]

See also[edit]


  1. ^ Jerris RC, Regnery RL (1996). "Will the real agent of cat-scratch disease please stand up?". Annu. Rev. Microbiol. 50: 707–25. doi:10.1146/annurev.micro.50.1.707. PMID 8905096.
  2. ^ Angelakis E, Raoult D. Pathogenicity and treatment of Bartonella infections. Int J Antimicrob Agents 2014;44:16–25.
  3. ^ Angelakis E, Raoult D. Pathogenicity and treatment of Bartonella infections. Int J Antimicrob Agents 2014;44:16–25.
  4. ^ Kavita Diddi; Rama Chaudhry; Nidhi Sharma; Benu Dhawan (28 March 2011). "Strategy for identification & characterization of Bartonella henselae with conventional & molecular methods". Indian Journal of Medical Research. 137 (2): 380–387. PMC 3657863. PMID 23563383.
  5. ^ Bernard La Scola; Didier Raoult (17 March 1999). "Culture of Bartonella quintana and Bartonella henselae from Human Samples: a 5-Year Experience (1993 to 1998)". Journal of Clinical Microbiology. 37 (6): 1899–1905. PMC 84980. PMID 10325344.
  6. ^ Parte, A.C. "Bartonella".
  7. ^ Mazur-Melewska, Katarzyna, et al. "Cat-scratch disease: a wide spectrum of clinical pictures." Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii 32.3 (2015): 216.

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