Bay R 1531

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Bay R 1531
Bay R 1531.svg
  • 1,3,4,5-tetrahydro-6-methoxy-N,N-dipropyl-benz[cd]indol-4-amine
CAS Number
PubChem CID
CompTox Dashboard (EPA)
Chemical and physical data
Molar mass288.435 g·mol−1
3D model (JSmol)
  • COc2ccc1[nH]cc3CC(Cc2c13)N(CCC)CCC
  • InChI=1S/C18H26N2O/c1-4-8-20(9-5-2)14-10-13-12-19-16-6-7-17(21-3)15(11-14)18(13)16/h6-7,12,14,19H,4-5,8-11H2,1-3H3

Bay R 1531 is a tricyclic tryptamine derivative which acts as a selective serotonin receptor 5-HT1A agonist. It was researched unsuccessfully for the treatment of stroke but remains in use for scientific research.[1][2][3][4]

See also[edit]


  1. ^ Bielenberg GW, Burkhardt M (December 1990). "5-hydroxytryptamine1A agonists. A new therapeutic principle for stroke treatment". Stroke. 21 (12 Suppl): IV161-3. PMID 2148035.
  2. ^ Critchley MA, Njung'e K, Handley SL (1992). "Actions and some interactions of 5-HT1A ligands in the elevated X-maze and effects of dorsal raphe lesions". Psychopharmacology. 106 (4): 484–90. doi:10.1007/bf02244819. PMID 1533721. S2CID 8404850.
  3. ^ Canto de Souza A, Nunes de Souza RL, Péla IR, Graeff FG (March 1997). "High intensity social conflict in the Swiss albino mouse induces analgesia modulated by 5-HT1A receptors". Pharmacology, Biochemistry, and Behavior. 56 (3): 481–6. doi:10.1016/s0091-3057(96)00246-8. PMID 9077586. S2CID 20078255.
  4. ^ Canto-de-Souza A, Nunes de Souza RL, Pelá IR, Graeff FG (March 1998). "Involvement of the midbrain periaqueductal gray 5-HT1A receptors in social conflict induced analgesia in mice". European Journal of Pharmacology. 345 (3): 253–6. doi:10.1016/s0014-2999(98)00018-1. PMID 9592023.