Bay R 1531

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Bay R 1531
BayR1531 structure.png
Identifiers
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
FormulaC18H28N2O
Molar mass288.427 g/mol g·mol−1
3D model (JSmol)

Bay R 1531 is a tricyclic tryptamine derivative which acts as a selective serotonin receptor 5-HT1A agonist. It was researched unsuccessfully for the treatment of stroke but remains in use for scientific research.[1][2][3][4]

See also[edit]

References[edit]

  1. ^ Bielenberg, G. W.; Burkhardt, M. (December 1990). "5-hydroxytryptamine1A agonists. A new therapeutic principle for stroke treatment". Stroke. 21 (12 Suppl): IV161–163. ISSN 0039-2499. PMID 2148035.
  2. ^ Critchley, M. A.; Njung'e, K.; Handley, S. L. (1992). "Actions and some interactions of 5-HT1A ligands in the elevated X-maze and effects of dorsal raphe lesions". Psychopharmacology. 106 (4): 484–490. doi:10.1007/bf02244819. ISSN 0033-3158. PMID 1533721.
  3. ^ Canto de Souza, A.; Nunes de Souza, R. L.; Péla, I. R.; Graeff, F. G. (March 1997). "High intensity social conflict in the Swiss albino mouse induces analgesia modulated by 5-HT1A receptors". Pharmacology Biochemistry and Behavior. 56 (3): 481–486. doi:10.1016/s0091-3057(96)00246-8. ISSN 0091-3057. PMID 9077586.
  4. ^ Canto-de-Souza, A.; Nunes de Souza, R. L.; Pelá, I. R.; Graeff, F. G. (1998-03-26). "Involvement of the midbrain periaqueductal gray 5-HT1A receptors in social conflict induced analgesia in mice". European Journal of Pharmacology. 345 (3): 253–256. doi:10.1016/s0014-2999(98)00018-1. ISSN 0014-2999. PMID 9592023.