Bengt I. Samuelsson
Bengt Ingemar Samuelsson
21 May 1934
|Alma mater||Stockholm University|
Bengt Ingemar Samuelsson (born 21 May 1934) is a Swedish biochemist. He shared with Sune K. Bergström and John R. Vane the 1982 Nobel Prize for Physiology or Medicine for discoveries concerning prostaglandins and related substances.
Education and early life
Research and career
Discussing the role of prostaglandins in the body, Samuelsson explained, "It's a control system for the cells that participates in many biological functions. There are endless possibilities of manipulating this system in drug development."
His research interests were originally in cholesterol metabolism with importance to reaction mechanisms. Following the structural work on prostaglandins along with Sune Bergström he was interested mainly in the transformation products of arachidonic acid. This has led to the identification of endoperoxides, thromboxanes and the leukotrienes, and his group has chiefly been involved in studying the chemistry, biochemistry and biology of these compounds and their function in biological control systems. This research has implications in numerous clinical areas, especially in thrombosis, inflammation, and allergy.
This field has grown enormously since those days. Between 1981 and 1995 about three thousand papers per year were published that specifically used the expression "prostaglandins," or related terms such as "prostacyclins," "leukotrienes," and "thromboxanes," in their labels and titles.
Awards and honors
In 1975, he was awarded the Louisa Gross Horwitz Prize from Columbia University together with Sune K. Bergström. He was elected a Foreign Member of the Royal Society (ForMemRS) in 1990.
- "Professor Bengt Samuelsson ForMemRS". London: Royal Society. Archived from the original on 2015-11-08.
- Raju, T N (1999), "The Nobel chronicles. 1982: Sune Karl Bergström (b 1916); Bengt Ingemar Samuelsson (b 1934); John Robert Vane (b 1927)", Lancet (published 27 November 1999), 354 (9193), p. 1914, doi:10.1016/s0140-6736(05)76884-7, PMID 10584758, S2CID 54236400
- Swedish Medical Association's Jubilee Award
- Bengt I. Samuelsson on Nobelprize.org including the Nobel Lecture From Studies of Biochemical Mechanisms to Novel Biological Mediators: Prostaglandin Endoperoxides, Thromboxanes and Leukotrienes