Benidipine

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Benidipine
Skeletal formula of benidipine
Ball-and-stick model of the benidipine molecule
Systematic (IUPAC) name
O5-methyl O3-[(3R)-1-(phenylmethyl)piperidin-3-yl] 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Clinical data
AHFS/Drugs.com International Drug Names
Routes of
administration
Oral
Identifiers
CAS Registry Number 105979-17-7 YesY
ATC code C08CA15
PubChem CID: 656668
ChemSpider 571013 N
UNII 4G9T91JS7E YesY
ChEMBL CHEMBL2218858 N
Chemical data
Formula C28H31N3O6
Molecular mass 505.57 g·mol−1
 N (what is this?)  (verify)

Benidipine (INN), also known as Benidipinum or benidipine hydrochloride, is a dihydropyridine calcium channel blocker for the treatment of high blood pressure (hypertension). It is a triple L-, T-, and N- type calcium channel blocker. It is reno- and cardioprotective.

Dosing[edit]

Benidipine is dosed as 2–4 mg once daily.[1]

Availability[edit]

Benidipine is sold as Coniel by Kyowa Hakko Kogyo.

Benidipine is only licensed for use in Japan and selected Southeast Asian countries, where it is sold as 4 mg tablets.

References[edit]

  1. ^ Hi-Eisai Pharmaceutical, Inc. "Coniel (benidipine) package insert (Philippines)". MIMS Philippines. CMPMedica. Retrieved 2008-03-31.